Rheumatoid immune diseases are diseases such as skin, joints, blood vessels and multiple systemic damage or abnormal immune function, which are mostly related to autoimmune abnormalities. Rheumatic Immunization is mainly to study the relationship between B cells, T cells, cytokines, adhesion molecules, acute phase reaction proteins and rheumatic diseases, and genes related to rheumatoid immunity, in order to reveal the incidence of rheumatic diseases. The mechanism ultimately achieves the purpose of diagnosing and treating rheumatic immune diseases.