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On the morning of Nov. 15th, the China Nucleic Acid International Forum (CNAF2018), which attracted the attention of the global nucleic acid industry, kicked off in Guangzhou Science City. The China Nucleic Acid International Forum is an internationally influential annual event for nucleic acids. The chairman of the conference are the world-renowned Nobel Prize winners. The forum aims to create a brand with international authoritative influence, and gathers well-known scientists, entrepreneurs and scholars from the global nucleic acid field to conduct high-end exchanges and dialogues. It is based on the bio-industry cluster of Guangdong, Hong Kong and Macao , serving the national production and research, and affecting global nucleic acid technology. With the transformation, focusing on the global results of nucleic acid drug creation and RNA research. The Forum has become one of the most influential nucleic acid forums in the world. It has been successfully held for six times so far and is known as the wind vane in the field of nucleic acid.

CNAF 2018

The forum was hosted by the Guangzhou Institute of Biomedicine and Health of the Chinese Academy of Sciences, the Guangzhou Workplace Leadership Group of Guangzhou Huangpu District, and the Guangzhou European and American Alumni Association. With the support of the Guangzhou Development Zone Science and Technology Innovation Bureau, RiboBio is responsible for hosting more than 20 big top speakers from the United States, Germany, Japan, Australia and other countries, including Nobel Prize winners, academicians of the Academy of Sciences, and internationally renowned scholars. The two-day forum attracted nearly 400 people from all over the world. CNAF2018, which is the special sub-forum of the 2nd Guanzhou International Biological Forum, is in sync with this “Davos Forum” focusing on the development of global bio-industry, in order to create a world-impact life science and bio-pharmaceutical industry. Eco-highland comprehensive help!

诺贝尔奖得主、美国科学院院士 Craig C. MELLO带来主旨报告

This year’s CNAF Forum focuses on 4 major themes: “The international frontier of non-coding RNA research”, “The latest developments in global nucleic acid drugs”, “Advanced technologies and applications in RNA research” and “The latest advances in nucleic acid diagnostics and markers.” On the opening day, a large number of giants in the field of nucleic acid were gathered: Craig C. MELLO, 2006 Nobel Prize in Physiology or Medicine, Fellow of the National Academy of Sciences, Director of the Institute of RNA Therapy at the University of Massachusetts Medical School, and Academician of the American Academy of Sciences, Professor of Stanford University School of Medicine Joseph PUGLISI, Fellow of the Australian Academy of Sciences, Andreas STRASSER, Senior Senior Fellow, Australian Eliza Hall Medical Institute, Mikiko C. SIOMI, Professor, University of Tokyo, Japan, Tetsuro HIROSE, Professor, Institute of Genetic Medicine, Hokkaido University, Japan, Senior Princess Margaret Cancer Center, Canada Scientist Houshen Hansen HE, Professor Chandrasekhar KANDURI, University of Gothenburg, Sweden, Professor Ailong KE, Cornell University, USA, Wei LI, Professor of Bioinformatics, Dan L. Duncan Cancer Center, Baylor College of Medicine, USA, Professor of Biochemistry, University of Konstanz, Germany Ekkehard LEBERER, Senior Director of R&D, Philippine University, Professor of Chengdu Sungkyunkwan University, Dong-ki LEE, Founder of OliX Pharmaceuticals, Zhen LI, Senior Vice President, Arrowhead Pharmaceuticals, USA, Muthiah MANO, Senior Vice President, Drug Development, Alnylam, USA HARAN, Laura SEPP-LORENZINO, Vice President, Vertex Pharmaceuticals, USA, Elisabetta Viani PUGLISI, Senior Scientist, Stanford University School of Medicine, Andrew YOO, Associate Professor, University of Washington, USA, Laura CROFT, Senior Research Fellow, Queensland University of Technology, Australia, Carina ANDERSSON, GE Global Product Manager, and Sirnaomics, USA Alan LU, executive vice president of the company.

The guests presented a fascinating report on RNAi therapeutics and delivery systems, mRNA regulation and epigenetic memory, lncRNA and cancer, RNA translation, nucleic acid structural biology frontiers, miRNA cell fate control and cells. Reprogramming factors, II-A CRISPR system, piRNA biological function, targeted MCL-1 cancer nucleic acid therapy, RNAi treatment of cardiovascular metabolic diseases and fibrotic diseases, HIV-1 reverse transcription complexes, etc. Participants benefited from an eye-opener and the participants were very enthusiastic.

According to the organizing committee, more than 150 institutions or units participated in the conference, including Peking University, Chinese Academy of Sciences, Zhejiang University, Shanghai Jiaotong University, Sichuan University, Beijing Cancer Hospital, Central South University, Wuhan University, University of Science and Technology of China, Sun Yat-sen University, Sun Yat-sen University Cancer Hospital, Jinan University, Southern Medical University, South China University of Technology, South China Agricultural University, Shenzhen University, Harbin Medical University, Nanchang University, Gansu Cancer Hospital, Shandong University, etc., as well as the Development Zone Development and Reform Bureau The leaders came to help out. The high-profile lineup of the forum also attracted more than a dozen sponsors including the Global 500 GE Healthcare Group, and was interviewed by the Guangzhou Daily and the well-known media such as Lilac Garden, TIMEDOO, Bio-Communication, Bio-Exploration, and China Bio-equipment Network. stand by. During the tea break at the forum, the participants were very active and the exchanges were very enthusiastic. The latest products and services brought by domestic and foreign companies were harvested, which promoted mutual trust and exchange between academic institutions and enterprises.

Selected outstanding poster winners

Under the great planning of the organizing committee of this forum and the active participation of the majority of nucleic acid researchers, the organizing committee selected a total of 14 academic wall newspapers and displayed them. During the conference, the international big coffee, including Nobel Prize winner Professor Craig C. MELLO and Professor of the American Academy of Sciences, Professor Joseph PUGLISI, also visited the wall newspaper area and the author. In the end, after voting, Qiyun Chen from the Institute of Life Sciences of the Shanghai Institute of Life Sciences, Shasha Chen of the Jiangmen Central Hospital, and Xichen Bao of the Guangzhou Institute of Biomedicine and Health of the Chinese Academy of Sciences won the honor of the outstanding academic wall newspaper. At the end of the forum (on the afternoon of the 16th), Professor Craig C. MELLO, the winner of the conference, presented the honorary certificate to the winners.

RiboBio to create a world-class CDMO/CMO service for oligonucleotide-based drugs

International guests visited Ribobio

RiboBio is Asia’s largest oligonucleotide-based drug manufacturer. Over the years, RiboBio has developed many novel nucleic-acid based technologies utilizing its world-class R&D team equipped with state-of-the-art tools and facilities. Currently, RiboBio develops and supplies innovative RNAi, lncRNA and miRNA products and offers as diverse line of oligonucleotide-based services including CRO, Synthesis and CDMO services from small to commercial scales. Our customers represent thousands from academia, medical, pharmaceutical, industrial and government organizations, both domestic and international. RiboBio was the first licensed cGMP manufacturing facility in China specializing in Oligonucleotide Manufacturing. In its facilities,
RiboBio offers a wide-range of synthesis scales for oligonucleotides, from milligram to multi-kilogram, with diverse modifications and chemistries. RiboBio manufactures oligonucleotides for various purposes including; pre-clinical research and toxicology studies, to clinical trials from Phase I to Phase III, and marketed-product commercialization of final API, diagnostic or
cosmetic ingredient. To assure the success of our manufacturing projects, we work closely with our clients: from the definition of the projects initial goals through development, including analytical methods development, tox and stability studies, through commercialization and beyond.

After the CNAF meeting on the first day, the guests visited the oligonucleotide cGMP manufacturing workshop, quality control laboratory and HCS & HCA laboratory, which impressed the visiting guests very much. 

Nucleic acids science plays a key role in precision medicine, genetic therapy and new solutions for human health. Continuous discovery of new RNA functions and constant emergence of innovative nucleic acids technologies are driving forces for the field and hold enormous promise for the future scientific and technological progress. The China Nucleic Acids Forum (CNAF) led by Nobel Prize winners is an international forum at the forefront of these developments, aims to push forward communications and collaborations in and abroad, and has been successfully held times since 2013. The CNAF has attracted high-profile speakers, including Nobel Prize winners, to highlight recent advances in nucleic-acid based medicine, scientific discoveries, diagnostics and industrial trends. It has been widely recognized as the premier forum in Asia for advancing nucleic acids research and drug development. The 2019 CNAF will feature 20+ globally prominent experts discussing the latest advances in nucleic acids research and development.

——China Nucleic Acid International Forum Organizing Committee

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