Chemical modification is able to change the physicochemical properties of oligonucleic acids, enhance the function of oligonucleic acids, and facilitate the study of how nucleic acids affect life phenomena. With an industry-leading team of scientists specializing in oligonucleic acid modification and synthesis, RiboBio is committed to creating a variety of modified oligonucleic acids to meet the needs for special chemically modified siRNAs.
1. Comprehensive coverage of various oligonucleic acid modification methods
2. Leading chemically-modified siRNA synthesis technology in China to ensure high quality
3. Professional synthesis team to provide a variety of customized chemically modified siRNA
Which siRNA is right for you?
RiboBio provides siRNA products for human, mouse, rat and other species for your selection.
Note: See Oligonucleic Acid Modification Directions for more chemical modification methods.
With a leading group of scientists specializing in the synthesis technology of chemically-modified oligonucleic acids, RiboBio creates a variety of modified oligonucleic acids, including end-labels and intermediate modifications. Thiophosphate skeleton, 2′-O-A Basement, 2′-O-fluoro, cholesterol, Cy3 and Cy5 labeling, biotin, amino, DNP and alkynyl modification are the common modifications, and their modification sites are shown below.
Figure 1: Schematic diagram of the common chemical modification sites for siRNA
Figure 2: Schematic diagram of the chemical modification methods for siRNA